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Molecular Biology / Strain Engineering (MSc./Ph.D)

Portugal, Braga, Braga

Job description

AI + Biology for sustainable ingredients

SilicoLife is a biotechnology company that harnesses the power of computational biology to sustainably produce valuable compounds through fermentation. Our proprietary technologies and expertise have been utilized by top companies in various industries for over a decade, as well as in research and development projects.

Recently, we received a Series A investment of 9.8 million euros, which will enable us to shift towards becoming a product-focused company. We will now exclusively use our technology and knowledge to create internal intellectual property and products for the high-growth supplements market.

Be part of something extraordinary and join us in our quest.

What’s the job?

We are seeking a highly motivated person with a committed personality for a position of Strain Engineer in our wet lab. You will perform wet lab activities in cell factory design and implementation projects, including strain and pathway design, DNA/strain construction, evaluation of strain performance, and pathway optimization and troubleshooting in E. coli and S. cerevisiae. Positions of different seniority levels available.

Job requirements


The successful candidate must have an M.Sc. or Ph.D. in Biological engineering, Biotechnology, Molecular Biology or a related discipline.

The candidate’s skills and qualifications will ideally include:

  • Excellent skills in Molecular Biology

  • Prior experience in strain engineering in E. coli and/or S. cerevisiae (experience with protein engineering tools is a plus)

  • Good knowledge of Bioinformatics and Systems Biology technologies (preferred)

  • Enthusiastic and innovative

  • Team player with strong interaction skills

  • Good communication capabilities (good knowledge of English language is a plus)

  • Ability to find creative solutions to new problems as they arise

  • Previous experience in running fermentations is a plus

  • Project / laboratory management experience will be considered for other positions

  • Interest in lab automation and use of liquid handling equipments (e.g. Opentrons, Hamilton) is a plus


You will work in close cooperation with the head of laboratory / head of development of the corresponding project and her/his duties involve the following:

  • Genetic design of strains to production and optimize target chemicals

  • Development of enzymes with higher catalytic performance

  • Implementation of strain engineering strategies to optimize production of target chemicals

  • Development of suitable cultivation conditions and analytical methods to assess the performance of the engineered strains

  • Present accurate project status to senior leadership, at both a summary and detailed level

  • Prepare technical documents used internally and externally to provide both summary and detailed technical information


Salary will be proposed considering the candidate experience. The selected candidate will be employed by the company and will be part of an interdisciplinary team of experts in computer science, artificial intelligence, bioinformatics, systems biology, molecular biology and bioprocess engineering.

Other benefits also include:

  • Flexible work schedule: great work/life balance

  • Extra vacation days over the 22 legally mandated

  • Participation in internal talks

  • Company retreats

  • Equipped kitchen and free coffee

You will be exposed to highly innovative projects combining world-class science with disruptive business models to create sustainable and economically viable solutions addressing global challenges.

SilicoLife is an equal opportunity employer that is committed to creating a diverse and inclusive workplace. We do not discriminate on the basis of race, gender, sexual orientation, religion, age, national origin, disability, or any other protected characteristic. We are dedicated to creating a workplace culture that values diversity, equity, and inclusion and that provides equal opportunities for all employees. We strive to foster a positive and supportive work environment for all, and we believe that everyone should have the opportunity to succeed, regardless of their background or identity. Our policies and practices reflect this commitment, and we are committed to treating all employees with respect and fairness.